“Blind Loop” Syndrome

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Altered myoelectric activity in the experimental blind loop syndrome.

Nutrient malabsorption and diarrhea are characteristic of the blind loop syndrome. Alterations in motility have been implicated as a cause of bacterial overgrowth, but the possibility that altered motility may result from alterations in the flora has not been explored. The purpose of this study was to characterize the myoelectric activity of the small intestine in the blind loop rat model. Eigh...

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Partial biliary obstruction with cholangitis producing a blind loop syndrome.

The frequency with which bacterial cholangitis complicates choledocholithiasis or benign postoperative biliary strictures has been the subject of several studies (Elkeles and Mirizzi, 1942; Anderson and Priestley, 1951; Edlund, Mollstedt, and Ouchterlony, 1959; Scott and Khan, 1967). The magnitude of the bacterial population present in this condition had, however, been crudely assessed until in...

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Kinetics of bile acid metabolism in experimental blind loop syndrome.

In an experimental model of the contaminated small bowel syndrome, Eriksson's washout technique was used to study bile salt metabolism. Bile salt secretion rate was increased from 204-7 +/- SD 36-5 mumol/100 g body weight/24 h to 329-9 +/- 146-6, pool size from 33-4 +/- 5-4 mumol/100 g BW to 42-5 +/- 7-2, and biliary flow from 6-6 +/- 1-72 ml/100 g BW/24 h to 8-4 +/- 2.1. Detailed analysis of t...

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Blind loop syndrome in children. Malabsorption secondary to intestinal stasis.

In experimental animals and in man, stasis of intestinal contents, particularly in the proximal portion of the small bowel, may produce malabsorption (Donaldson, 1964; Hoet and Eyssen, 1964). The syndrome originally described by Cannon and Murphy (1906) referred to the clinical picture produced by stasis consequent to a side-to-side intestinal anastomosis. The term 'blind loop syndrome' now is ...

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Pathogenesis of mucosal injury in the blind loop syndrome. Brush border enzyme activity and glycoprotein degradation.

The effect of intestinal bacterial over-growth on brush border hydrolases and brush border glycoproteins was studied in nonoperated control rats, control rats with surgically introduced jejunal self-emptying blind loops, and rats with surgically introduced jejunal self-filling blind loops. Data were analyzed from blind loop segments, segments above and below the blind loops, and three correspon...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1959

ISSN: 0035-9157

DOI: 10.1177/003591575905200107